Rome, Florence, and Naples had inherited the masterpieces of antiquity; and the manuscripts of AEschylus, Sophocles, and Euripides had come (thanks to the conquest of Mahomet II) to rejoin the statue of Xanthippus and the works of Phidias and Praxiteles.

The principal sovereigns of Italy had come to understand, when they let their eyes dwell upon the fat harvests, the wealthy villages, the flourishing manufactories, and the marvellous churches, and then compared with them the poor and rude nations of fighting men who surrounded them on all sides, that some day or other they were destined to become for other countries what America was for Spain, a vast gold-mine for them to work.
In consequence of this, a league offensive and defensive had been signed, about 1480, by Naples, Milan, Florence, and Ferrara, prepared to take a stand against enemies within or without, in Italy or outside.

Ludovico Sforza, who was more than anyone else interested in maintaining this league, because he was nearest to France, whence the storm seemed to threaten, saw in the new pope's election means not only of strengthening the league, but of making its power and unity conspicuous in the sight of Europe..