The cardinal had every one of them dismissed, with orders to quit Rome within twenty-four hours and the Roman territories within three days.

The poor wretches had all collected together to obey the order, with their wives and children and baggage, on the Piazza of St.Peter, when suddenly, by Cardinal Valentino's orders, they were hemmed in on all sides by two thousand Spaniards, who began to fire on them with their guns and charge them with their sabres, while Caesar and his mother looked down upon the carnage from a window.

In this way they killed fifty or perhaps sixty; but the rest coming up, made a charge at the assassins, and then, without suffering any loss, managed to beat a retreat to a house, where they stood a siege, and made so valiant a defense that they gave the pope time--he knew nothing of the author of this butchery--to send the captain of his guard to the rescue, who, with a strong detachment, succeeded in getting nearly forty of them safely out of the town: the rest had been massacred on the piazza or killed in the house.
But this was no real and adequate revenge; for it did not touch Charles himself, the sole author of all the troubles that the pope and his family had experienced during the last year.

So Caesar soon abandoned vulgar schemes of this kind and busied himself with loftier concerns, bending all the force of his genius to restore the league of Italian princes that had been broken by the defection of Sforza, the exile of Piero dei Medici, and the defeat of Alfonso.

The enterprise was more easily accomplished than the pope could have anticipated.