The reference here is to the review on the "Origin of Species" generally believed to be by the late Sir R.Owen, and published in the April number of the "Edinburgh Review," 1860.

Owen's biographer is silent on the subject, and prints, without comment, the following passage in an undated letter from Sedgwick to Owen: "Do you know who was the author of the article in the "Edinburgh" on the subject of Darwin's theory?
On the whole, I think it very good.

I once suspected that you must have had a hand in it, and I then abandoned that thought.

I have not read it with any care" (Owen's "Life," Volume II., page 96).
April 9th [1860].
I never saw such an amount of misrepresentation.

At page 530 (98/2.
"Lasting and fruitful conclusions have, indeed, hitherto been based only on the possession of knowledge; now we are called upon to accept an hypothesis on the plea of want of knowledge.