In the Virginia Gazette of December 1, 1768, Henderson must have read with astonishment not unmixed with dismay that "the Six Nations and all their tributaries have granted a vast extent of country to his majesty, and the Proprietaries of Pennsylvania, and settled an advantageous boundary line between their hunting country and this, and the other colonies to the Southward as far as the Cherokee River, for which they received the most valuable present in goods and dollars that was ever given at any conference since the settlement of America." The news was now bruited about through the colony of North Carolina, that the Cherokees were hot in their resentment because the Northern Indians, the inveterate foes of the Cherokees and the perpetual disputants for the vast Middle Ground of Kentucky, had received at the Treaty of Fort Stanwix, November 5, 1768, an immense compensation from the crown for the territory which they, the Cherokees, claimed from time immemorial.

Only three weeks before, John Stuart, Superintendent for Indian Affairs in the Southern Department, had negotiated with the Cherokees the Treaty of Hard Labor, South Carolina (October 14th), by which Governor Tryon's line of 1767, from Reedy River to Tryon Mountain, was continued direct to Colonel Chiswell's mine, the present Wytheville, Virginia, and thence in a straight Brie to the mouth of the Great Kanawha.

Thus at the close of the year 1768 the crown through both royal governor and superintendent of Indian affairs acknowledged in fair and open treaty the right of the Cherokees, whose Tennessee villages guarded the gateway, to the valley lands east of the mountain barrier as well as to the dim mid-region of Kentucky.

In the very act of negotiating the Treaty of Fort Stanwix, Sir William Johnson privately acknowledged that possession of the trans-Alleghany could be legally obtained only by extinguishing the title of the Cherokees.
These conflicting claims soon led to collisions between the Indians and the company's settlers.

In the spring of 1769 occurred one of those incidents in the westward advance which, though slight in itself, was to have a definite bearing upon the course of events in later years.