He was seriously injured by the open defection of Horace Greeley.
Not able, or even desirous, to appear on the New-York delegation, Mr.Greeley sat in the convention as a representative from Oregon.
The old firm of Seward, Weed, and Greeley, according to his own humorous expression, had been dissolved by the withdrawal of the junior partner; and a bitter dissension had in fact existed for six years without public knowledge.

With his great influence in the agricultural regions of the country, Mr.Greeley was enabled to turn a strong current of popular feeling against the eminent senator from New York.

Mr.Seward sustained further injury by the action of the States which were regarded as politically doubtful.
Pennsylvania and Indiana took part against him.

Henry S.Lane had just been nominated for governor of Indiana, with Oliver P.Morton -- not then known beyond his State--for lieutenant-governor.

It was understood that Lane would be sent to the Senate if the Republicans should carry the State, and that Morton, whose strength of character was known and appreciated at home, would become governor.