The new husband was Carlo Canale, of Mantua.
[Illustration: CHURCH OF S.MARIA DEL POPOLO, ROME.] Before he came to Rome he had by his attainments acquired some reputation among the humanists of Mantua.

There is still extant a letter to Canale, written by the young poet Angelo Poliziano regarding his _Orfeo_; the manuscript of this, the first attempt in the field of the drama which marked the renaissance of the Italian theater, was in the hands of Canale, who, appreciating the work of the faint-hearted poet, was endeavoring to encourage him.[9] At the suggestion of Cardinal Francesco Gonzaga, a great patron of letters, Poliziano had written the poem in the short space of two days.

Carlo Canale was the cardinal's chamberlain.

The _Orfeo_ saw the light in 1472.

When Gonzaga died, in 1483, Canale went to Rome, where he entered the service of Cardinal Sclafetano, of Parma.