Her connection with the Vatican, the mystery which surrounded her, and the fate she suffered, make her one of the most fascinating women of her age.

Doubtless there are buried in various libraries numerous verses dedicated to her by the Roman poets who must have swarmed at the court of the Pope's daughter to render homage to her beauty and to seek her patronage.
In Rome, Lucretia had an opportunity to enjoy, if she were so disposed, the society of many brilliant men, for even during the sovereignty of the Borgias the Muses were banished neither from the Vatican nor from Rome.

It can not be denied, however, that the daughters of princely houses were allowed to devote themselves to the cultivation of the intellect more freely at the secular courts of Italy than they were at the papal court.

Not until Lucretia went to Ferrara to live was she able to endeavor to emulate the example of the princesses of Mantua and Urbino.

While living in Rome she was too young and her environment too narrow for her to have had any influence upon the literary and aesthetic circles of that city, although, owing to her position, she must have been acquainted with them.
Her father was not incapable of intellectual pleasures; he had his court minstrels and poets.