Having perfect confidence in the intelligence, the fidelity, and probity of the Duchess, which We have dwelt upon in previous letters, and likewise in your unfailing obedience to Us and to the Holy See, We trust that you will receive the Duchess Lucretia, as is your duty, with all due honor as your regent, and show her submission in all things.

As We wish her to be received and accepted by you with special honor and respect, so do We command you in this epistle--as you value Our favor and wish to avoid Our displeasure--to obey the Duchess Lucretia, your regent, in all things collectively and severally, in so far as law and custom dictate in the government of the city, and whatever she may think proper to exact of you, even as you would obey Ourselves, and to execute her commands with all diligence and promptness, so that your devotion may receive due approbation.

Given in Rome, in St.Peter's, under the papal seal, August 8, 1499.
HADRIANUS (Secretary).[65] Lucretia left Rome for her new home the same day.

She set out with a large retinue, and accompanied by her brother Don Giuffre; Fabio Orsini, now the consort of Girolama Borgia, her kinswoman; and a company of archers.

She left the Vatican mounted on horseback, the governor of the city, the Neapolitan ambassador, and a number of other gentlemen forming an escort to act as a guard of honor, while her father took a position in a loggia over the portal of the palace of the Vatican to watch his departing daughter and her cavalcade.