Her regency there was merely intended to signify the actual taking possession of the territory which Alexander desired to bestow upon his daughter.
In the meantime her husband Alfonso had decided, unfortunately for himself, to obey Alexander's command and return to his wife--perhaps because he really loved her.

The Pope ordered him to go to Spoleto by way of Foligno, and then to come with his spouse to Nepi, where he himself intended to be.

The purpose of this meeting was to establish his daughter as sovereign there also.
Nepi had never been a baronial fief, although the prefects of Vico and the Orsini had held the place at different times.

The Church through its deputies governed the town and surrounding country.

When Alexander was a cardinal his uncle Calixtus had made him governor of the city, and such he remained until he was raised to the papal throne, when he conferred Nepi upon Cardinal Ascanio Sforza.