The victors immediately forced a peace on most advantageous terms.
Not until the conclusion of the war did Lucretia's husband return to Rome.

We shall see him again there, for the last time, at the Easter festivities of 1497, when, as Alexander's son-in-law, he assumed his official place during the celebration in S.Peter's, and, standing near Caesar and Gandia, received the Easter palm from the Pope's hand.

His position in the Vatican had, however, become untenable; Alexander was anxious to dissolve his marriage with Lucretia.

Sforza was asked to give her up of his own free will, and, when he refused, was threatened with extreme measures.
Flight alone saved him from the dagger or poison of his brothers-in-law.
According to statements of the chroniclers of Pesaro, it was Lucretia herself who helped her husband to flee and thus caused the suspicion that she was also a participant in the conspiracy.

It is related that, one evening when Jacomino, Lord Giovanni's chamberlain, was in Madonna's room, her brother Caesar entered, and on her command the chamberlain concealed himself behind a screen.