He accompanied King Ferrante on his flight, and also followed his standard when, after the retreat of Charles VIII, he, with the help of Spain, Venice, and the Pope, again secured possession of his kingdom, entering Naples in the summer of 1495.
Not until the following year did Don Giuffre and his wife come to Rome.
In royal state they entered the Eternal City, May 20, 1496.

The ambassadors, cardinals, officers of the city, and numerous nobles went to meet them at the Lateran gate.

Lucretia also was there with her suite.

The young couple were escorted to the Vatican.

The Pope on his throne, surrounded by eleven cardinals, received his son and daughter-in-law.