Giovan Simone, another brother, born in 1479, led a vagabond life until he joined Buonarroto in a cloth business that was bought for them by Michael Angelo.

Sigismondo, born in 1481, was a soldier.

At the age of forty he settled down on the small paternal farm at Settignano, and became a mere peasant, very much to the annoyance and chagrin of his famous brother, Michael Angelo, who spent his earnings for the advantage of his brothers, and the advancement of his family, with a kindness and generosity as beautiful as it is rare.

Francesca, the mother of Michael Angelo and of the other sons of Lodovico Buonarroti, was married to him in 1472.

When she died is not known, but Lodovico married his second wife Lucrezia in 1485.