Columbus (1490-1559) did much in correcting the mistakes made in the anatomy of the bones as described by Vesalius.

He also added much to the science by giving correct accounts of the shape and cavities of the heart, and made many other discoveries of minor importance.

Fallopius (1523-1562) added considerably to the general knowledge of anatomy, made several discoveries in the anatomy of the ear, and also several organs in the abdominal cavity.
At this time a most vitally important controversy was in progress as to whether or not the veins of the bodies were supplied with valves, many anatomists being unable to find them.

Etienne had first described these structures, and Vesalius had confirmed his observations.

It would seem as if there could be no difficulty in settling the question as to the fact of such valves being present in the vessels, for the demonstration is so simple that it is now made daily by medical students in all physiological laboratories and dissecting-rooms.