Another of his sons, Giovanni, received the honor of the Cardinalship.

The one was destined to compromise the ascendency of his family in Florence for a period of eighteen years, the other was destined to re-establish that ascendency on a new and more despotic basis.

Piero had not his father's prudence, and could not maintain himself in the delicate position of a commercial and civil tyrant.

During the disturbances caused by the invasion of Charles VIII.

he was driven with all his relatives into exile.