By and by she began to feel tired, and at last gave way quite abruptly, ceased to menstruate five years before I saw her, grew pale and feeble, and dropped in weight in six months from one hundred and twenty-five pounds to ninety-five.

Nature had at last its revenge.

Everything wearied her,--to eat, to drive, to read, to sew.
Walking became impossible, and, tied to her couch, she grew dyspeptic and constipated.

The asthenopia which is almost constantly seen in such cases added to her trials, because reading had to be abandoned, and so at last, despite unusual vigor of character, she gave way to utter despair, and became at times emotional and morbid in her views of life.
After numberless forms of treatment had been used in vain, she came to this city and passed into my care.
At this time she could not walk more than a few steps without flushing and without a sense of painful tire.

Her morning temperature was 97.5 deg.
F., and her white corpuscles were perhaps a third too numerous.