Six months later she died in Scotland.
Marriage for the king was necessary, and David Beaton, later Cardinal Beaton and Archbishop of St Andrews, obtained for his lord a lady coveted by Henry VIII., Mary, of the great Catholic house of Lorraine, widow of the Duc de Longueville, and sister of the popular and ambitious Guises.
The pair were wedded on June 10, 1538; there was fresh offence to Henry and a closer tie to the Catholic cause.

The appointment of Cardinal Beaton (1539) to the see of St Andrews, in succession to his uncle, gave James a servant of high ecclesiastical rank, great subtlety, and indomitable resolution, but remote from chastity of life and from clemency to heretics.

Martyrdoms became more frequent, and George Buchanan, who had been tutor of James's son by Margaret Erskine, thought well to open a window in a house where he was confined, walk out, and depart to the Continent.

Meanwhile Henry, no less than Beaton, was busily burning his own martyrs.

In 1539 Henry renewed his intercourse with James, attempting to shake his faith in David Beaton, and to make him rob his Church.