At one moment, Margaret and Angus fled to England where was born her daughter Margaret, later Lady Lennox and mother of Henry Darnley.
Angus, with Home, now recrossed the Border (1516), and was reconciled to Albany; against all unity in Scotland Henry intrigued, bribing with a free hand, his main object being to get Albany sent out of the country.
In early autumn, 1516, Home, the leader of the Borderers at Flodden, and his brother were executed for treason; in June, 1517, Albany went to seek aid and counsel in France; when the queen-mother returned from England to Scotland, where, if she retained any influence, she might be useful to her brother's schemes.

But, contrary to Henry's interests, in this year Albany renewed the old alliance with France; while, in 1518, the queen- mother desired to divorce Angus.

But Angus was a serviceable tool of Henry, who prevented his sister from having her way; and now the heads of the parties in the distracted country were Arran, chief of the Hamiltons, and Beaton, Archbishop of Glasgow, standing for France; and Angus representing the English party.
Their forces met at Edinburgh in the street battle of "Cleanse the Causeway," wherein the Archbishop of Glasgow wore armour, and the Douglases beat the Hamiltons out of the town (April 30, 1520).

Albany returned (1521), but the nobles would not join with him in an English war (1522).

Again he went to France, while Surrey devastated the Scottish Border (1523).