Cruel, moody, and jealous, he passed his life in perpetual terror.

His nephews, Galeazzo and Barnabas, conspired against him, and were exiled to Flanders.

His wife, Isabella Fieschi, intrigued with Galeazzo and disgraced him by her amours with Ugolino Gonzaga and Dandolo the Doge of Venice.

Finally suspicion rose to such a pitch between this ill-assorted couple, that, while Lucchino was plotting how to murder Isabella, she succeeded in poisoning him in 1349.

In spite of these domestic calamities, Lucchino was potent as a general and governor.