This alteration of structure does not constitute a disease, provided the harmonious relation of the organism with the environment be not impaired.

An individual without a liver should not be regarded as diseased, provided there can be such an internal adjustment that all of the vital phenomena could go on in the usual manner without the aid of this useful and frequently maligned organ.2.It is _individual_.

In the varying degrees of exposure to unfavorable conditions of a more serious nature some, but not all, of the organisms are destroyed; in the slight exposure, few; in the longer, many.

Unfavorable conditions which will destroy all individuals of a species exposed to them must be extremely rare.[1] There is no such individuality in non-living things.

In a mass of sugar grains each grain shows just the same characteristics and reacts in exactly the same way as all the other grains of the mass.