Indian nature would seem to be a nature apart and distinct.

The red men, unless in suffering or oppression, will not listen to what they call "the smooth honey words of the pale-faced sages;" and even when they do so, they argue upon every dogma and point of faith, and remain unconvinced.
The missionaries, therefore, after a time, contented themselves with practising deeds of charity, with alleviating their sufferings when able, from their knowledge of medicine and surgery, and by moral precepts, softening down as much as they could the fierce and occasionally cruel tempers of this wild untutored race.
Among other advantages which the Shoshones derived from our missionaries, was the introduction of vaccination.

At first it was received with great distrust, and indeed violently opposed, but the good sense of the Indians ultimately prevailed: and I do not believe that there is one of the Soshones born since the settlement was formed who has not been vaccinated: the process was explained by the Padres Marini and Polidori to the native medical men, and is now invariably practised by them.
I may as well here finish the histories of the good missionaries.

When I was sent upon an expedition to Monterey, which I shall soon have to detail, Padre Marini acccompanied me.

Having failed with the Shoshones, he considered that he might prove useful by locating himself in the Spanish settlements of California.