CHRYSIPPUS, from Soli in Cilicia (290--207 B.C.), followed Cleanthes, and, in his voluminous writings, both defended and modified the Stoical creed.

These three represent the _first_ period of the system.

The _second_ period (200--50 B.C.) embraces its general promulgation, and its introduction to the Romans.
Chrysippus was succeeded by ZENO of Sidon, and DIOGENES of Babylon; then followed ANTIPATER, of Tarsus, who taught PANAETIUS of Rhodes (d.
112 B.C.), who, again, taught POSIDONIUS of Apamea, in Syria.

(Two philosophers are mentioned from the native province of St.Paul, besides Chrysippus--ATHEKODOEUS, from Cana in Cilicia; and ARCHEDEMUS, from Tarsus, the apostle's birthplace.

It is remarked by Sir A.Grant, that almost all the first Stoics were of Asiatic birth; and the system itself is undeniably more akin to the oriental mind than to the Greek.) Posidonius was acquainted with Marius and Pompey, and gave lessons to Cicero, but the moral treatise of Cicero, _De Officiis_, is derived from a work of Panaetius.