A young Florentine about to be put to death by an order of Pope Sixtus V was so overcome with grief that he shed bloody tears and sweated blood.

The Ephemerides contains many instances of bloody tears and sweat occasioned by extreme fear, more especially fear of death.

Mezeray mentions that the detestable Charles IX of France, being under constant agitation and emotion, sank under a disorder which was accompanied by an exudation of blood from every pore of his body.
This was taken as an attempt of nature to cure by bleeding according to the theory of the venesectionists.

Fabricius Hildanus mentions a child who, as a rule, never drank anything but water, but once, contrary to her habit, drank freely of white wine, and this was soon followed by hemorrhage from the gums, nose, and skin.
There is a case also related of a woman of forty-five who had lost her only son.

One day she fancied she beheld him beseeching her to release his soul from purgatory by prayers and fasting every Friday.