For two years he suffered with debility, fatigue, bronchitis, night-sweats, headache, and great thirst.

Mentally he was dull; the bones of the face and extremities showed the hypertrophies characteristic of acromegaly, the soft parts not being involved.

The circumference of the trunk at the nipples was 62 inches, and over the most prominent portion of the kyphosis and pigeon-breast, 74 inches.
The authors agree with Dana and others that there is an intimate relation between acromegaly and gigantism, but they go further and compare both to the growth of the body.

They call attention to the striking resemblance to acromegaly of the disproportionate growth of the boy at adolescence, which corresponds so well to Marie's terse description of this disease: "The disease manifests itself by preference in the bones of the extremities and in the extremities of the bones," and conclude with this rather striking and aphoristic proposition: "Acromegaly is gigantism of the adult; gigantism is acromegaly of adolescence." The many theories of the cause of gigantism will not be discussed here, the reader being referred to volumes exclusively devoted to this subject.
Celebrated Giants .-- Mention of some of the most famous giants will be made, together with any associate points of interest.
Becanus, physician to Charles V, says that he saw a youth 9 feet high and a man and a woman almost 10 feet.

Ainsworth says that in 1553 the Tower of London was guarded by three brothers claiming direct descent from Henry VIII, and surnamed Og, Gog, and Magog, all of whom were over 8 feet in height.