Hentzschel speaks of a man with congenital absence of the iris who had five children, three of whom exhibited the same anomaly while the others were normal.

Benson, Burnett, Demaux, Lawson, Morison, Reuling, Samelson, and others also report congenital deficiency of the irides in both eyes.
Jeaffreson describes a female of thirty, living in India, who was affected with complete ossification of the iris.

It was immovable and quite beautiful when seen through the transparent cornea; the sight was only slightly impaired.

No cause was traceable.
Multiple Pupils .-- More than one pupil in the eye has often been noticed, and as many as six have been seen.

They may be congenital or due to some pathologic disturbance after birth.