[Anomalies and Curiosities of Medicine by George M. Gould]@TWC D-Link bookAnomalies and Curiosities of Medicine CHAPTER XV 25/151
In this case there was neither pain nor tenderness. Prudden reports the case of a girl of twenty-five who, during convalescence from variola, became paraplegic, and during this time multiple neuromata appeared.
At the postmortem more than a thousand tumors were found affecting not only the peripheral branches and the sympathetic, but also the cranial nerves and the pneumogastric.
Under the microscope these tumors showed an increase in the interfascicular as well as perivascular fibers, but the nerve-fibers were not increased in size or number.
Virchow collected 30 cases of multiple neurofibromata.
In one case he found 500, in another from 800 to 1000 tumors. Plexiform neuroma is always congenital, and is found most frequently in the temporal region, the neck, and the sides of the face, but almost any part of the body may be affected.
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