The patient was a young girl of seventeen who had several times missed her menstruation, and who was considered pregnant.

The abdomen was more developed than usual in a young woman.

The breasts were voluminous, and the nipples surrounded by a somber areola.

At certain periods after the cessation of menstruation, she had incontinence of urine, and had also repeatedly vomited.

The urine was of high specific gravity, albuminous, alkaline, and exhaled a disagreeable odor.