He had recourse to it in March, 1796, for sleeplessness; in the following November, for relief from violent nervous pains; and near the close of the Stowey period, in May, 1798, when the vagaries of Lloyd, the estrangement from Lamb, domestic anxiety, and physical suffering had reduced him to a state of extreme nervous wretchedness, he again took refuge in opiates, of which "Kubla Khan" is partly the result.

He returned from Germany in 1799, worked for a while on a newspaper in London and on a translation of Schiller's "Wallenstein," and in the summer of 1800 removed to Keswick in Cumberland, in the Lake Country, where the Wordsworths had already established themselves.

Here, in the autumn of 1800, he strove to finish "Christabel," and did finish the second part.

In the winter and spring he suffered from a complicated illness, in which he again had recourse to laudanum; and from the spring of 1801 he was confirmed in the opium habit, sinking often to pitiful depths of moral and physical misery.

He was in the Mediterranean, chiefly at Malta, from 1804 to 1806.