Lorenzo's son, Pier Francesco de' Medici, had a son Giovanni de' Medici.

This Giovanni, who married Caterina Sforza of Milan, had also a son named Giovanni, born in 1498, and it was he who was the rightful heir when Lorenzo, Duke of Urbino, died in 1519.

He was connected with both sides of the family, for his father, as I have said, was the great grandson of the first Medici on our list, and his wife was Maria Salviati, daughter of Lucrezia de' Medici--herself a daughter of Lorenzo the Magnificent--and Jacopo Salviati, a wealthy Florentine.

When, however, Lorenzo, Duke of Urbino, died in 1519, Giovanni was a young man of twenty-one with an absorbing passion for fighting, which Clement VII (then Giulio) was only too keen to foster, since he wished him out of the way in order that his own projects for the ultimate advancement of the base-born Alessandro, and meanwhile of the catspaw, the base-born Ippolito, might be furthered.

Giovanni had already done some good service in the field, was becoming famous as the head of his company of Black Bands, and was known as Giovanni delle Bande Nere; and his marriage to his cousin Maria Salviati and the birth of his only son Cosimo in 1519 made no difference to his delight in warfare.