Its first aim is to destroy all sense of high moral and religious responsibility.

It reduces man to a mere machine.

It cuts him off from his Maker, it hides from him the laws of God, and leaves him to grope his way from time to eternity in the dark, under the arbitrary and despotic control of a frail, depraved, and sinful fellow-man.

As the serpent-charmer of India is compelled to extract the deadly teeth of his venomous prey before he is able to handle him with impunity, so the slaveholder must strike down the conscience of the slave before he can obtain the entire mastery over his victim.
It is, then, the first business of the enslaver of men to blunt, deaden, and destroy the central principle of human responsibility.

Conscience is, to the individual soul, and to society, what the law of gravitation is to the universe.