He derived a stupendous income from his numerous abbeys in Italy and Spain, his three bishoprics of Valencia, Porto, and Carthage, and his ecclesiastical offices, among which the Vice-Chancellorship alone yielded him annually eight thousand florins.( 1) 1 The gold florin, ducat, or crown was equal to ten shillings of our present money, and had a purchasing power of five times that amount.
Volterra refers with wonder to the abundance of his plate, to his pearls, his gold embroideries, and his books, the splendid equipment of his beds, the trappings of his horses, and other similar furnishings in gold, in silver, and in silk.

In short, he was the wealthiest prince of the Church of his day, and he lived with a magnificence worthy of a king or of the Pope himself.
Of the actual man, Volterra, writing in 1586, says: "He is of a spirit capable of anything, and of a great intelligence.

A ready speaker, and of distinction, notwithstanding his indifferent literary culture; naturally astute, and of marvellous talent in the conduct of affairs." In the year in which Volterra wrote of Cardinal Roderigo in such terms Vannozza was left a widow by the death of Giorgio della Croce.

Her widowhood was short, however, for in the same year--on June 6--she took a second husband, possibly at the instance of Roderigo Borgia, who did not wish to leave her unprotected; that, at least, is the general inference, although there is very little evidence upon which to base it.
This second husband was Carlo Canale, a Mantovese scholar who had served Cardinal Francesco Gonzaga in the capacity of chamberlain, and who had come to Rome on the death of his patron.
The marriage contract shows that by this time Vannozza had removed her residence to Piazza Branchis.

In addition to this she had by this time acquired a villa with its beautiful gardens and vine-yards in the Suburra near S.Pietro in Vincoli.