Unfortunately the young couple were not destined to many years of life together, as in 1483 both died.
Of Cesare all that we know at this period is what we learn from the Papal Bulls conferring several benefices upon him.

In July 1482 he was granted the revenues from the prebendals and canonries of Valencia; in the following month he was appointed Canon of Valencia and apostolic notary.

In April 1484 he was made Provost of Alba, and in September of the same year treasurer of the Church of Carthage.

No doubt he was living with his mother, his brothers, and his sister at the house in the Piazza Pizzo di Merlo, where an ample if not magnificent establishment was maintained.
By this time Cardinal Roderigo's wealth and power had grown to stupendous proportions, and he lived in a splendour well worthy of his lofty rank.

He was now fifty-three years of age, still retaining the air and vigour of a man in his very prime, which, no doubt, he owed as much as to anything to his abstemious and singularly sparing table-habits.