The Pope took the only course possible under the awkward circumstances, and refused to see the ambasssador.

Thereupon the offended King of France held a grand council "in which were proposed and treated many things against the Pope and for the reform of the Church." These royal outbursts of Christianity, these pious kingly frenzies to unseat an unworthy Pontiff and reform the Church, follow always, you will observe, upon the miscarriage of royal wishes.
In the Consistory of September 1493 the Pope created twelve new cardinals to strengthen the Sacred College in general and his own hand in particular.
Amongst these new creations were the Pope's son Cesare, and Alessandro Farnese, the brother of the beautiful Giulia.

The grant of the red hat to the latter appears to have caused some scandal, for, owing to the Pope's relations with his sister, to which it was openly said that Farnese owed the purple, he received the by-name of Cardinal della Gonella--Cardinal of the Petticoat.
That was the first important step in the fortunes of the House of Farnese, which was to give dukes to Parma, and reach the throne of Spain (in the person of Isabella Farnese) before becoming extinct in 1758..