The toll of life among the settlers was heavy.

Many of the best-known border leaders were slain.

Food and powder often ran short.

Corn might be planted, but whether it would be harvested or not the planters never knew; and the hunter's rifle shot, necessary though it was, proved only too often an invitation to the lurking foe.

But sometimes, through all the dangers of forest and trail, Daniel Boone slipped away silently to Harrodsburg to confer with Clark; or Clark himself, in the Indian guise that suited the wild man in him not ill, made his way to and from the garrisons which looked to him for everything.
Twice Clark gathered together the "guns" of Kentucky and, marching north into the enemy's country, swept down upon the Indian towns of Piqua and Chillicothe and razed them.