And among the young Kentuckians enlisted by William Clark were sons of the sturdy fighters of still an earlier border line, Clinch and Holston Valley men who had adventured under another Lewis at Point Pleasant.

Daniel would recognize in these--such as Charles Floyd--the young kinsmen of his old-time comrades whom he had preserved from starvation in the Kentucky wilderness by the kill from his rifle as they made their long march home after Dunmore's War.
In May, Lewis and Clark's pirogues ascended the Missouri and the leaders and men of the expedition spent another day in La Charette.

Once again, at least, Daniel was to watch the westward departure of pioneers.

In 1811, when the Astorians passed, one of their number pointed to the immobile figure of "an old man on the bank, who, he said, was Daniel Boone." Sometimes the aged pioneer's mind cast forward to his last journey, for which his advancing years were preparing him.

He wrote on the subject to a sister, in 1816, revealing in a few simple lines that the faith whereby he had crossed, if not more literally removed, mountains was a fixed star, and that he looked ahead fearlessly to the dark trail he must tread by its single gleam.