This occurred apparently during the winter of 1748-49.

In the spring of 1750 we see the whole Boone family (save two sons) with their wives and children, their household goods and their stock, on the great highway, bound for a land where the hot heart and the belligerent spirit shall not be held amiss.
Southward through the Shenandoah goes the Boone caravan.

The women and children usually sit in the wagons.

The men march ahead or alongside, keeping a keen eye open for Indian or other enemy in the wild, their rifles under arm or over the shoulder.

Squire Boone, who has done with Quakerdom and is leading all that he holds dear out to larger horizons, is ahead of the line, as we picture him, ready to meet first whatever danger may assail his tribe.